Safety and tolerability of the hexadecapeptide AOD9604 in humans
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There has not been a UL (upper intake level) established for B12 because it is not stored in your body and therefore, can not build up enough to cause serious adverse side effects for most people
Other lipotropics include choline, inositol, and betaine (trimethylglycine), all of which help prevent the accumulation of fat in the liver and thus ensure normal liver function, which is essential for the elimination of toxins from the body
doi:10.1016/j.bcp.2018.05.003 Neelakantan H, Brightwell CR, Graber TG, et al
These conditions prevent the body from adequately absorbing oral B12 through the digestive tract